get_lead_snps() Get the top variants within 1 MB windows of the genome with association p-values below the given threshold
Usage
get_sign_and_sugg_loci(
df,
genome_wide_thresh = 5e-08,
suggestive_thresh = 1e-06,
flank_size = 1e+06,
region_size = 1e+06
)Arguments
- df
Dataframe, GWAS summary statistics
- genome_wide_thresh
A number. P-value threshold for genome wide significant loci (5e-08 by default)
- suggestive_thresh
A number. P-value threshold for suggestive loci (1e-06 by default)
- flank_size
A number (default = 1e6). The size of the flanking region for the significant and suggestitve snps.
- region_size
A number (default = 1e6). The size of the region for top snp search. Only one snp per region is returned.